2012 · Genomics and biotechnology
Martin Jinek, Emmanuelle Charpentier, Jennifer Doudna et al.
The study reconstituted RNA-guided Cas9 DNA cleavage and demonstrated that targeting could be programmed through guide RNA.
Representative work
RNA-guided Cas9 endonuclease study
A Programmable Dual-RNA–Guided DNA Endonuclease (2012)